Medtronic Heart Fellowship

James Edelman BSc (Hons) MBBS (Hons)

PhD Candidate

Dr James Edelman was awarded the inaugural Medtronic Heart Fellowship in 2010. He is a trainee in Cardiothoracic Surgery and the Medtronic Fellowship has enabled him to take time away from clinical training to undertake his PhD full-time at the University of Sydney, under the supervision of Associate Professor Michael Vallely and Professor Paul Bannon.

Dr Edelman’s PhD project is titled Inflammation, Tissue Injury and Thrombosis in Off-pump Coronary Artery Bypass Grafting. The aim is to better understand thrombotic complications after surgery, and the processes linking injury with inflammation and coagulation. Divided into three parts, the project focuses on 1) novel inflammatory markers and cellular responses that are altered after cardiac surgery, and may contribute to the systemic inflammatory response syndrome; 2) the alterations in coagulation that follow surgery, and may put patients at risk of either post-operative bleeding or thrombosis; and 3) the prevention of neurologic injury in coronary artery bypass grafting by using the ‘an aortic’, off-pump technique.

Some early findings from the project have been published in peer-reviewed journals and presented at the Annual Scientific Meetings of the Australasian Society of Cardiothoracic Surgery and Cardiac Society of Australia and New Zealand. James is a Clinical Associate Lecturer at the University of Sydney and regularly teaches students in the Graduate Medical Program at the Sydney Medical School.