Davies RA, Black D, Jeremy RW, Bannon PG, Bayfield MS, Hendel PN, Hughes CF, Wilson MK, Vallely MP

Heart Lung Circ 2011 Nov;20(11):704-11

PMID: 21872527

Abstract

BACKGROUND: Aortic arch replacement is a complicated and high risk procedure. There have been many advances over recent years. We review the changes in our unit’s techniques and outcomes over the past 22 years.

METHODS: Data were collated from databases and medical records for all patients who underwent aortic arch replacement surgery from January 1989 to December 2010. The patients were divided into two groups – Group A (1989-2005) and Group B (2006-2010). Data were analysed to compare early and late series patients’ outcomes. Logistic regression was used to identify variables that predicted mortality.

RESULTS: Seventy-five eligible patients (56 males; mean age: 57.5 years; Group A: 40, Group B 35) were identified. There were great changes in the technique and the methods of cerebral protection. The overall mortality rate was 30.7% – Group A: 50% and Group B: 8.6% (p<0.001). Overall permanent neurological dysfunction was 23.7% – Group A: 40% and Group B: 11.8% (p=0.012). Cardiovascular disease and circulatory arrest time were significant predictors of mortality.

CONCLUSIONS: Increased experience and volume and advances in techniques over 22 years have resulted in major improvements in outcomes for patients having aortic arch replacement, allowing the procedure to be performed with greatly improved outcomes.