Research

Cao C, Wang D, Tian DH, Wilson-Smith A, Huang J, Rimner A J Thorac Dis 2019 Dec;11(12):5187-5198 PMID: 32030236 Abstract Background: There is growing evidence to support the hypothesis that radical treatment of pulmonary oligometastatic disease with stereotactic body radiation therapy (SBRT) can improve oncological outcomes. However, some reports suggest colorectal cancer (CRC) pulmonary metastases…

Zentner D, James P, Bannon P, Jeremy R Heart Lung Circ 2020 Apr;29(4):607-618 PMID: 32067919 Abstract Aortopathies are conditions that result in aortic dilatation, aneurysm formation and dissection. Familial aortopathies (perhaps better known as heritable thoracic aortic aneurysm and dissection, h-TAAD, as not all have a positive family history) are recognised to have an underlying…

Myles PS, Smith JA, Kasza J, Silbert B, Jayarajah M, Painter T, Cooper DJ, Marasco S, McNeil J, Bussières JS, McGuinness S, Byrne K, Chan MTV, Landoni G, Wallace S, Forbes A, J. Thorac. Cardiovasc. Surg. 2019 02;157(2):644-652.e9 PMID: 30459103 Abstract BACKGROUND: Tranexamic acid reduces blood loss and transfusion requirements in cardiac surgery but may…

Callaghan FM, Bannon P, Barin E, Celemajer D, Jeremy R, Figtree G, Grieve SM J Magn Reson Imaging 2019 01;49(1):90-100 PMID: 30102443 Abstract BACKGROUND: Abnormal flow dynamics play an early and causative role in pathologic changes of the ascending aorta. PURPOSE: To identify: 1) the changes in flow, shape, and size that occur in the…

Kay S, Moore BM, Moore L, Seco M, Barnes C, Marshman D, Grieve SM, Celermajer DS Heart Lung Circ 2020 Feb;29(2):196-201 PMID: 31494040 Abstract BACKGROUND: Prompted by a cluster of observations concerning ascending aortic pathology in elite rugby players, we assessed over 150 asymptomatic predominantly retired players with echocardiography, aiming to document the prevalence and…

Carelli M, Seco M, Forrest P, Wilson MK, Vallely MP, Ramponi F Perfusion 2019 11;34(8):717-720 PMID: 31046596 Abstract In recent years, extracorporeal membrane oxygenation has become increasingly common in the treatment of in-hospital cardiac arrest in non-cardiac surgery patients. This includes cardiac arrest secondary to perioperative anaphylactic shock refractory to standard advanced life support protocols,…

Chakos A, Ferret P, Muston B, Yan TD, Tian DH Ann Cardiothorac Surg 2020 Jan;9(1):1-9 PMID: 32175234 Abstract Background: While extended criteria lung donation has helped expand the lung donor pool, utilization of lungs from donors of at least one other solid organ is still limited to around 15-30%. Ex-vivo lung perfusion (EVLP) offers the…

Wilson-Smith AR, Kim YS, Evans GE, Yan TD Ann Cardiothorac Surg 2020 Jan;9(1):10-19 PMID: 32175235 Abstract Background: Lung transplantation has long been the accepted therapy for end-stage pulmonary fibrotic disease. Presently, there is an ongoing debate over whether single or bilateral transplantation is the most appropriate treatment for end-stage disease, with a paucity of high-quality…

Tian DH, Wilson-Smith A, Koo SK, Forrest P, Kiat H, Yan TD Heart Lung Circ 2019 Jun;28(6):844-849 PMID: 30773323 Abstract BACKGROUND: Antegrade cerebral perfusion (ACP) is an essential adjunct for prolonged hypothermic circulatory arrest (HCA) during aortic arch surgery. However, it has yet to be established whether ACP should be delivered unilaterally or bilaterally. The…