Research Publications

Our primary focus at The Baird Institute is to encourage and fund research to improve the surgical outcomes and quality of life for patients facing heart or lung surgery. The funds we raise go directly to research that improves the surgical procedures associated with heart and lung surgery. Improvements can include less intrusive procedures as well as techniques that improve survival rates.

Below you will find a list of publications that our surgeons and research fellows have been involved in writing.

Surgical Pulmonary Embolectomy: Experience in a Series of 37 Consecutive Cases

Edelman JJ, Okiwelu N, Anvardeen K, Joshi P, Murphy B, Sanders LH, Newman MA, Passage J Heart Lung Circ 2016 Dec;25(12):1240-1244 PMID: 27423976 Abstract BACKGROUND: Massive pulmonary embolism is a poorly tolerated condition. Treatment options in this condition include anticoagulation and primary reperfusion therapy – systemic thrombolysis, catheter based treatments or surgical embolectomy. There is…

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Veno-Arterial ECMO in the Setting of Post-Infarct Ventricular Septal Defect: A Bridge to Surgical Repair

McLaughlin A, McGiffin D, Winearls J, Tesar P, Cole C, Vallely M, Clarke A, Fraser J Heart Lung Circ 2016 Nov;25(11):1063-1066 PMID: 27374861 Abstract Extracorporeal membrane oxygenation (ECMO) is a complex rescue therapy utilised to provide circulatory and/or respiratory support to critically ill patients who have failed maximal conventional therapy. The use of ECMO in…

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The Aortic Root Replacement Procedure: 12-year Experience from the Australian and New Zealand Society of Cardiac and Thoracic Surgeons Database

Dhurandhar V, Parikh R, Saxena A, Vallely MP, Wilson MK, Black DA, Tran L, Reid CM, Bannon PG Heart Lung Circ 2016 Dec;25(12):1245-1251 PMID: 27269475 Abstract BACKGROUND: The aortic root replacement procedure (ARR), is often considered the gold standard in the management of aortic root and ascending aorta aneurysms. Our aim was to review the…

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KCa1.1, a calcium-activated potassium channel subunit alpha 1, is targeted by miR-17-5p and modulates cell migration in malignant pleural mesothelioma

Cheng YY, Wright CM, Kirschner MB, Williams M, Sarun KH, Sytnyk V, Leshchynska I, Edelman JJ, Vallely MP, McCaughan BC, Klebe S, van Zandwijk N, Lin RC, Reid G Mol. Cancer 2016 Jun;15(1):44 PMID: 27245839 Abstract BACKGROUND: Malignant pleural mesothelioma (MPM) is an aggressive, locally invasive, cancer elicited by asbestos exposure and almost invariably a…

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Early and Late Outcomes Following Valve Sparing Aortic Root Reconstruction: The ANZSCTS Database

Dhurandhar V, Parikh R, Saxena A, Vallely MP, Wilson MK, Black DA, Tran L, Reid C, Bannon PG Heart Lung Circ 2016 May;25(5):505-11 PMID: 26795638 Abstract BACKGROUND: Valve sparing aortic root reconstruction (VSARR) has become an alternative to traditional aortic root replacement with a valved conduit. There have been various modifications but the two broad…

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Mechanical Versus Bioprosthetic Aortic Valve Replacement in Middle-Aged Adults: A Systematic Review and Meta-Analysis

Zhao DF, Seco M, Wu JJ, Edelman JB, Wilson MK, Vallely MP, Byrom MJ, Bannon PG Ann. Thorac. Surg. 2016 Jan; PMID: 26794881 Abstract The choice of a bioprosthetic valve (BV) or mechanical valve (MV) in middle-aged adults undergoing aortic valve replacement is a complex decision that must account for numerous prosthesis and patient factors. A systematic…

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Best Practice BioBanking of Human Heart Tissue

Lal S, Li A, Allen D, Allen PD, Bannon P, Cartmill T, Cooke R, Farnsworth A, Keogh A, Dos Remedios C Biophys Rev 2015 Dec;7(4):399-406 PMID: 26998172 Abstract This review provides a guide to researchers who wish to establish a biobank. It also gives practical advice to investigators seeking access to samples of healthy or…

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A proteomics-based approach identifies secreted protein acidic and rich in cysteine as a prognostic biomarker in malignant pleural mesothelioma

Kao SC, Kirschner MB, Cooper WA, Tran T, Burgers S, Wright C, Korse T, van den Broek D, Edelman J, Vallely M, McCaughan B, Pavlakis N, Clarke S, Molloy MP, van Zandwijk N, Reid G Br. J. Cancer 2016 Mar;114(5):524-31 PMID: 26889976 Abstract BACKGROUND: We aimed to identify prognostic blood biomarkers using proteomics-based approaches in…

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