Research Publications
Our primary focus at The Baird Institute is to encourage and fund research to improve the surgical outcomes and quality of life for patients facing heart or lung surgery. The funds we raise go directly to research that improves the surgical procedures associated with heart and lung surgery. Improvements can include less intrusive procedures as well as techniques that improve survival rates.
Below you will find a list of publications that our surgeons and research fellows have been involved in writing.
Veno-Arterial ECMO in the Setting of Post-Infarct Ventricular Septal Defect: A Bridge to Surgical Repair
McLaughlin A, McGiffin D, Winearls J, Tesar P, Cole C, Vallely M, Clarke A, Fraser J Heart Lung Circ 2016 Nov;25(11):1063-1066 PMID: 27374861 Abstract Extracorporeal membrane oxygenation (ECMO) is a complex rescue therapy utilised to provide circulatory and/or respiratory support to critically ill patients who have failed maximal conventional therapy. The use of ECMO in…
The Aortic Root Replacement Procedure: 12-year Experience from the Australian and New Zealand Society of Cardiac and Thoracic Surgeons Database
Dhurandhar V, Parikh R, Saxena A, Vallely MP, Wilson MK, Black DA, Tran L, Reid CM, Bannon PG Heart Lung Circ 2016 Dec;25(12):1245-1251 PMID: 27269475 Abstract BACKGROUND: The aortic root replacement procedure (ARR), is often considered the gold standard in the management of aortic root and ascending aorta aneurysms. Our aim was to review the…
KCa1.1, a calcium-activated potassium channel subunit alpha 1, is targeted by miR-17-5p and modulates cell migration in malignant pleural mesothelioma
Cheng YY, Wright CM, Kirschner MB, Williams M, Sarun KH, Sytnyk V, Leshchynska I, Edelman JJ, Vallely MP, McCaughan BC, Klebe S, van Zandwijk N, Lin RC, Reid G Mol. Cancer 2016 Jun;15(1):44 PMID: 27245839 Abstract BACKGROUND: Malignant pleural mesothelioma (MPM) is an aggressive, locally invasive, cancer elicited by asbestos exposure and almost invariably a…
Early and Late Outcomes Following Valve Sparing Aortic Root Reconstruction: The ANZSCTS Database
Dhurandhar V, Parikh R, Saxena A, Vallely MP, Wilson MK, Black DA, Tran L, Reid C, Bannon PG Heart Lung Circ 2016 May;25(5):505-11 PMID: 26795638 Abstract BACKGROUND: Valve sparing aortic root reconstruction (VSARR) has become an alternative to traditional aortic root replacement with a valved conduit. There have been various modifications but the two broad…
Mechanical Versus Bioprosthetic Aortic Valve Replacement in Middle-Aged Adults: A Systematic Review and Meta-Analysis
Zhao DF, Seco M, Wu JJ, Edelman JB, Wilson MK, Vallely MP, Byrom MJ, Bannon PG Ann. Thorac. Surg. 2016 Jan; PMID: 26794881 Abstract The choice of a bioprosthetic valve (BV) or mechanical valve (MV) in middle-aged adults undergoing aortic valve replacement is a complex decision that must account for numerous prosthesis and patient factors. A systematic…
Best Practice BioBanking of Human Heart Tissue
Lal S, Li A, Allen D, Allen PD, Bannon P, Cartmill T, Cooke R, Farnsworth A, Keogh A, Dos Remedios C Biophys Rev 2015 Dec;7(4):399-406 PMID: 26998172 Abstract This review provides a guide to researchers who wish to establish a biobank. It also gives practical advice to investigators seeking access to samples of healthy or…
A proteomics-based approach identifies secreted protein acidic and rich in cysteine as a prognostic biomarker in malignant pleural mesothelioma
Kao SC, Kirschner MB, Cooper WA, Tran T, Burgers S, Wright C, Korse T, van den Broek D, Edelman J, Vallely M, McCaughan B, Pavlakis N, Clarke S, Molloy MP, van Zandwijk N, Reid G Br. J. Cancer 2016 Mar;114(5):524-31 PMID: 26889976 Abstract BACKGROUND: We aimed to identify prognostic blood biomarkers using proteomics-based approaches in…
The Benefits and Pitfalls of the Use of Risk Stratification Tools in Cardiac Surgery
Saxena A, Dhurandhar V, Bannon PG, Newcomb AE Heart Lung Circ 2016 Apr;25(4):314-8 PMID: 26857968 Abstract Risk assessment tools are increasingly used in surgery. In cardiac surgery, risk models are used for patient counselling, surgical decision-making, performance benchmarking, clinical research, evaluation of new therapies and quality assurance, among others. However, they have numerous disadvantages which…
