Research Publications

Our primary focus at The Baird Institute is to encourage and fund research to improve the surgical outcomes and quality of life for patients facing heart or lung surgery. The funds we raise go directly to research that improves the surgical procedures associated with heart and lung surgery. Improvements can include less intrusive procedures as well as techniques that improve survival rates.

Below you will find a list of publications that our surgeons and research fellows have been involved in writing.

High-Sensitivity Troponin I after Cardiac Surgery and 30-Day Mortality

Background: Consensus recommendations regarding the threshold levels of cardiac troponin elevations for the definition of perioperative myocardial infarction and clinically important periprocedural myocardial injury in patients undergoing cardiac surgery range widely (from >10 times to ≥70 times the upper reference limit for the assay). Limited evidence is available to support these recommendations. Methods: We undertook an international…

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Impact of distal aortic perfusion on ‘segmental steal’ depleting spinal cord blood flow-a quantitative experimental approach

Objectives: Aortic steal is an underestimated risk factor for intraoperative spinal cord ischaemia. A negative effect on spinal cord perfusion in thoraco-abdominal aneurysm repair has been suspected if blood drains away from the cord initiated by a reversal of the arterial pressure gradient. The amount of blood and pressure loss via back-bleeding of segmental arteries and…

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Aorto-cavitary fistula: a rare case of Enterobacter cloacae infective endocarditis complicated by aortic root abscess and fistula to the right ventricle

Enterobacter cloacae are a rare cause of infective endocarditis (IE). We present an interesting case of a 51-year-old intravenous drug user with E. cloacae IE of a prosthetic aortic valve and a fistula into the right ventricle. He underwent surgical repair and 6 weeks of intravenous meropenem.

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Surgery for infective endocarditis following low-intermediate risk transcatheter aortic valve replacement-a multicentre experience

Objectives: With the expansion of transcatheter aortic valve replacement (TAVR) into intermediate and low risk, the number of TAVR procedures is bound to rise and along with it the number of cases of infective endocarditis following TAVR (TIE). The aim of this study was to review a multicentre experience of patients undergoing surgical intervention for TIE…

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Incorporating the anterior mitral leaflet to the annulus impairs left ventricular function in an ovine model

Abstract Objectives Transcatheter mitral valve prostheses are designed to capture the anterior leaflet and surgical techniques designed to fully preserve the subvalvular apparatus at prosthetic valve insertion both serve to shorten the anterior mitral leaflet height, thus effectively incorporating it into the anterior annulus. This study quantifies the acute effects of incorporating the anterior mitral…

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Bioprosthetic interstrut distance subtending the preserved anterior mitral leaflet mitigates left ventricular outflow tract obstruction

Abstract Background The anterior mitral leaflet (AML) contributes to left ventricular (LV) function but is normally excised at the time of a bioprosthetic valve insertion. This study aimed to investigate methods of safely retaining the AML at the time of mitral valve replacement. Methods Five adult sheep (57 ± 3.8 kg) each underwent 3 insertions of a bioprosthetic…

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Sutureless Versus Rapid Deployment Aortic Valve Replacement: Results From a Multicenter Registry

Background: This study compared clinical and hemodynamic in-hospital outcomes of patients undergoing sutureless vs rapid deployment aortic valve replacement (SURD-AVR) in the large population of the Sutureless and Rapid Deployment International Registry (SURD-IR). Methods: We examined 4695 patients who underwent isolated or combined SURD-AVR. The “sutureless” Perceval valve (LivaNova PLC, London, United Kingdom) was used in 3133…

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