Research Publications

Our primary focus at The Baird Institute is to encourage and fund research to improve the surgical outcomes and quality of life for patients facing heart or lung surgery. The funds we raise go directly to research that improves the surgical procedures associated with heart and lung surgery. Improvements can include less intrusive procedures as well as techniques that improve survival rates.

Below you will find a list of publications that our surgeons and research fellows have been involved in writing.

A Comparison of the Demographics and Surgical Risk Scores of Patients Undergoing Isolated Surgical and Trans-Catheter Aortic Valve Replacements at Royal Prince Alfred Hospital. Heart, Lung and Circulation, Vol. 28, S332. (2019)

Introduction: Definitive management of severe aortic stenosis has evolved rapidly. Indications for trans-catheter procedures have progressed from patients deemed inoperable to high risk and now to patients representing intermediate surgical risk. Health resource availability also are determinants on treatment received. Advanced age and high surgical risk impact resource use through higher costs and length of…

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Bicuspid Aortic Valve Disease-Valve Morphotype Influences Age at and Indications for Operative Treatment. Heart, Lung and Circulation 28(4):S347. (2019)

Introduction: Patients with BAV are heterogeneous and risk prediction for the complications of valvulopathy and/or aortopathy remains challenging. Methods: Adult patients who had undergone aortic or aortic valve surgery for BAV were identified from our Adult Congenital Heart and Cardiothoracic Surgery databases. BAV morphology was classified according to the number of raphes present according to…

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The 2CHEER Study:(Mechanical CPR, Hypothermia, ECMO and Early Re-Perfusion) for Refractory Cardiac arrest. Heart, Lung and Circulation 28:S322. (2019)

Aims: Retrospective studies have suggested improved survival outcomes with the use of Extracorporeal membrane oxygenation (ECMO) in refractory cardiac arrest (ECPR). We sought to prospectively assess outcomes in refractory cardiac arrest treated with ECPR. Methods: The 2CHEER trial (mechanical CPR, Hypothermia, ECMO and Early Reperfusion) is a multi-centre, prospective cohort study conducted at Royal Prince…

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Successful Management of Severe Liver Laceration Secondary to Lund University Cardiopulmonary Assist System Cardiopulmonary Resuscitation Complicated by Systemic Heparin for Extracorporeal Membrane Oxygenation and Dual Antiplatelets After ST Elevation Myocardial Infarction. Heart, Lung and Circulation 28:S130 (2019)

Out-of-hospital cardiac arrest (OOHCA) is a significant cause of mortality, with regionally pooled survival until discharge ranging from 3.0–9.7%. Early and effective cardiopulmonary resuscitation (CPR) remains crucial to improving overall survival, and mechanical CPR has been proposed as a method with which to improve its quality and consistency. Outcomes of mechanical CPR are mixed, and…

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Development of a Local Thoracic Surgical Database. Heart, Lung and Circulation 28:S126-127. (2019)

Purpose: A high volume of thoracic surgery is performed in Australia and New Zealand each year, although no national database exists for the routine capture of clinical outcomes. A thoracic surgery database would allow clinical research, internal hospital auditing, hospital benchmarking, development of risk prediction models, and assessment of healthcare resource utilisation.

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No-Air Direct Innominate Artery Cannulation Technique for Aortic Arch Surgery. Heart, Lung and Circulation 28:S118. (2019)

Introduction: Aortic arch procedures require reliable cerebral protection to reduce the incidence of neurological complications, some of which may be due to the introduction of air into the cerebral circulation. For selective antegrade cerebral perfusion, this study described a simple yet novel direct innominate artery cannulation technique designed to eliminate the incidence of air embolism.

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Thirty-Day Stroke Risk After Anaortic Off-Pump Coronary Artery Bypass Grafting Versus Percutaneous Coronary Intervention: A Network Meta-Analysis. Heart, Lung and Circulation 28:S117. (2019)

Purpose: There are no studies comparing 30-day stroke risk following anaortic off-pump coronary artery bypass grafting (anOPCABG) vs percutaneous coronary intervention (PCI). A network meta-analysis was performed to indirectly compare 30-day stroke risk following anOPCABG vs PCI.

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Mortality Following Off-Pump Versus On-Pump Coronary Artery Bypass Grafting at Five-Year Follow-Up: A Meta-Analysis. Heart, Lung and Circulation 28:S106. (2019)

Purpose: Long-term mortality following off-pump vs on-pump coronary artery bypass grafting (CABG) remains controversial, despite recent randomised controlled trials. A systematic review and meta-analysis were performed to assess mortality risk at 5-year follow-up.

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