Research Publications

Our primary focus at The Baird Institute is to encourage and fund research to improve the surgical outcomes and quality of life for patients facing heart or lung surgery. The funds we raise go directly to research that improves the surgical procedures associated with heart and lung surgery. Improvements can include less intrusive procedures as well as techniques that improve survival rates.

Below you will find a list of publications that our surgeons and research fellows have been involved in writing.

Tranexamic acid in coronary artery surgery: One-year results of the Aspirin and Tranexamic Acid for Coronary Artery Surgery (ATACAS) trial

Myles PS, Smith JA, Kasza J, Silbert B, Jayarajah M, Painter T, Cooper DJ, Marasco S, McNeil J, Bussières JS, McGuinness S, Byrne K, Chan MTV, Landoni G, Wallace S, Forbes A, J. Thorac. Cardiovasc. Surg. 2019 02;157(2):644-652.e9 PMID: 30459103 Abstract BACKGROUND: Tranexamic acid reduces blood loss and transfusion requirements in cardiac surgery but may…

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Age-related changes of shape and flow dynamics in healthy adult aortas: A 4D flow MRI study

Callaghan FM, Bannon P, Barin E, Celemajer D, Jeremy R, Figtree G, Grieve SM J Magn Reson Imaging 2019 01;49(1):90-100 PMID: 30102443 Abstract BACKGROUND: Abnormal flow dynamics play an early and causative role in pathologic changes of the ascending aorta. PURPOSE: To identify: 1) the changes in flow, shape, and size that occur in the…

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Rugby Player’s Aorta: Alarming Prevalence of Ascending Aortic Dilatation and Effacement in Elite Rugby Players

Kay S, Moore BM, Moore L, Seco M, Barnes C, Marshman D, Grieve SM, Celermajer DS Heart Lung Circ 2020 Feb;29(2):196-201 PMID: 31494040 Abstract BACKGROUND: Prompted by a cluster of observations concerning ascending aortic pathology in elite rugby players, we assessed over 150 asymptomatic predominantly retired players with echocardiography, aiming to document the prevalence and…

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Extracorporeal membrane oxygenation support in refractory perioperative anaphylactic shock to rocuronium: a report of two cases

Carelli M, Seco M, Forrest P, Wilson MK, Vallely MP, Ramponi F Perfusion 2019 11;34(8):717-720 PMID: 31046596 Abstract In recent years, extracorporeal membrane oxygenation has become increasingly common in the treatment of in-hospital cardiac arrest in non-cardiac surgery patients. This includes cardiac arrest secondary to perioperative anaphylactic shock refractory to standard advanced life support protocols,…

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Ex-vivo lung perfusion versus standard protocol lung transplantation-mid-term survival and meta-analysis

Chakos A, Ferret P, Muston B, Yan TD, Tian DH Ann Cardiothorac Surg 2020 Jan;9(1):1-9 PMID: 32175234 Abstract Background: While extended criteria lung donation has helped expand the lung donor pool, utilization of lungs from donors of at least one other solid organ is still limited to around 15-30%. Ex-vivo lung perfusion (EVLP) offers the…

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Single versus double lung transplantation for fibrotic disease-systematic review

Wilson-Smith AR, Kim YS, Evans GE, Yan TD Ann Cardiothorac Surg 2020 Jan;9(1):10-19 PMID: 32175235 Abstract Background: Lung transplantation has long been the accepted therapy for end-stage pulmonary fibrotic disease. Presently, there is an ongoing debate over whether single or bilateral transplantation is the most appropriate treatment for end-stage disease, with a paucity of high-quality…

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Unilateral Versus Bilateral Antegrade Cerebral Perfusion: A Meta-Analysis of Comparative Studies

Tian DH, Wilson-Smith A, Koo SK, Forrest P, Kiat H, Yan TD Heart Lung Circ 2019 Jun;28(6):844-849 PMID: 30773323 Abstract BACKGROUND: Antegrade cerebral perfusion (ACP) is an essential adjunct for prolonged hypothermic circulatory arrest (HCA) during aortic arch surgery. However, it has yet to be established whether ACP should be delivered unilaterally or bilaterally. The…

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Temperature Selection in Antegrade Cerebral Perfusion for Aortic Arch Surgery: A Meta-Analysis

Tian DH, Weller J, Hasmat S, Preventza O, Forrest P, Kiat H, Yan TD Ann. Thorac. Surg. 2019 07;108(1):283-291 PMID: 30682350 Abstract BACKGROUND: The increasing use of antegrade cerebral perfusion (ACP) during aortic arch surgery has corresponded with a trend toward warmer target temperatures for hypothermic circulatory arrest. This meta-analysis examined the clinical outcomes using…

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