Research

Characterization of the hypercoagulable state following severe orthopedic trauma

White AE, Edelman JJ, Lott N, Bannon PG, McElduff P, Curnow JL, Balogh ZJ J Trauma Acute Care Surg 2014 Aug;77(2):231-7 PMID: 25058247 Abstract BACKGROUND: Acute traumatic coagulopathy develops in seriously injured patients, which is followed by a paradoxical hypercoagulable state. The hypercoagulable state contributes to venous thromboembolism, and yet, there are no sensitive tests…

Natural history of hypercoagulability in patients undergoing coronary revascularization and effect of preoperative myocardial infarction

Edelman JJ, Reddel CJ, Kritharides L, Bannon PG, Fraser JF, Curnow JL, Vallely MP J. Thorac. Cardiovasc. Surg. 2014 Aug;148(2):536-43 PMID: 24280714 Abstract OBJECTIVES: The balance between hyper- and hypocoagulable states is critical after coronary artery surgery both with (coronary artery bypass grafting [CABG]) and without (off-pump coronary artery bypass [OPCAB]) cardiopulmonary bypass to prevent…

Systematic review of the cost-effectiveness of transcatheter aortic valve implantation

Indraratna P, Ang SC, Gada H, Yan TD, Manganas C, Bannon P, Cao C J. Thorac. Cardiovasc. Surg. 2014 Aug;148(2):509-14 PMID: 24280719 Abstract OBJECTIVE: Transcatheter aortic valve implantation (TAVI) has emerged as an alternative treatment to aortic valve replacement (AVR) for selected patients with severe aortic stenosis. The present systematic review was conducted to analyze…

Transapical aortic valve implantation – an Australian experience

Seco M, Martinez G, Bannon PG, Cartwright BL, Adams M, Ng M, Wilson MK, Vallely MP Heart Lung Circ 2014 May;23(5):462-8 PMID: 24315653 Abstract BACKGROUND: The aim of this study was to report our initial experience with the transapical approach to transcatheter aortic valve implantation (TAVI) at an Australian institution. METHODS: All patients with severe,…

The silent and apparent neurological injury in transcatheter aortic valve implantation study (SANITY): concept, design and rationale

Fanning JP, Wesley AJ, Platts DG, Walters DL, Eeles EM, Seco M, Tronstad O, Strugnell W, Barnett AG, Clarke AJ, Bellapart J, Vallely MP, Tesar PJ, Fraser JF BMC Cardiovasc Disord 2014;14:45 PMID: 24708720 Abstract BACKGROUND: The incidence of clinically apparent stroke in transcatheter aortic valve implantation (TAVI) exceeds that of any other procedure performed…

Immobilisation of a fibrillin-1 fragment enhances the biocompatibility of PTFE

Hajian H, Wise SG, Bax DV, Kondyurin A, Waterhouse A, Dunn LL, Kielty CM, Yu Y, Weiss AS, Bilek MM, Bannon PG, Ng MK Colloids Surf B Biointerfaces 2014 Apr;116:544-52 PMID: 24572497 Abstract Current vascular biomaterials exhibit poor biocompatibility characterised by failure to promote endothelialisation, predisposition to neoinitmal hyperplasia and excessive thrombogenicity. Fibrillin-1, a major…

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