Research Publications

Our primary focus at The Baird Institute is to encourage and fund research to improve the surgical outcomes and quality of life for patients facing heart or lung surgery. The funds we raise go directly to research that improves the surgical procedures associated with heart and lung surgery. Improvements can include less intrusive procedures as well as techniques that improve survival rates.

Below you will find a list of publications that our surgeons and research fellows have been involved in writing.

Preventing Sheep Carotid Artery Spasm for Vascular Graft Surgery and Computed Tomography Angiography

The development of small-diameter vascular grafts requires testing in large animal models before advancing to clinical trials. Vascular graft interposition implantation in sheep carotid arteries (CAs) is the most widely used model, but ovine CAs are prone to severe spasm following surgical manipulation, potentially impairing graft performance assessment. There is paucity in the literature on…

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Cellular heterogeneity of pluripotent stem cell-derived cardiomyocyte grafts is mechanistically linked to treatable arrhythmias

Preclinical data have confirmed that human pluripotent stem cell-derived cardiomyocytes (PSC-CMs) can remuscularize the injured or diseased heart, with several clinical trials now in planning or recruitment stages. However, because ventricular arrhythmias represent a complication following engraftment of intramyocardially injected PSC-CMs, it is necessary to provide treatment strategies to control or prevent engraftment arrhythmias (EAs)….

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Systematic review and meta-analysis of two decades of reported outcomes for robotic coronary artery bypass grafting

Background: Despite the well-documented safety and feasibility of robotic coronary artery bypass grafting (CABG), widespread adoption of this approach remains limited by its steep learning curve, high procedural costs and paucity of data on longer-term efficacy. This current meta-analysis aims to provide a systematic overview of the outcomes of robot-assisted CABG, with a focus on long…

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Predictors of surgical intervention in first episode primary spontaneous pneumothorax requiring chest drain insertion

Background: Primary spontaneous pneumothorax occurs in patients with no underlying lung disease and guidelines recommend chest tube drainage for the first episode, with surgical intervention reserved for recurrent episodes, persistent air leak or failure of lung re-expansion. Modern surgical management is associated with reduced length of hospital stay and superior freedom from recurrence compared with chest…

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Incidence and Outcomes of Emergency Intraprocedural Surgical Conversion During Transcatheter Aortic Valve Implantation: A Multicentric Analysis

No abstract available

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Comparison of modified Del Nido and Custodiol® cardioplegia in minimally invasive mitral valve surgery

Objectives: In this study, we evaluated if modified Del Nido cardioplegia delivers comparable cardiac protection in comparison to Custodiol® in patients undergoing isolated minimally invasive mitral valve repair. Methods: From January 2018 to October 2021, all patients undergoing non-emergent isolated minimally invasive mitral valve repair were included in this study. The cardioplegia was chosen at the surgeons’…

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Extrapleural pneumonectomy for sarcoma: Outcomes of adult patients at a specialized center

Background: Extrapleural pneumonectomy (EPP) is a complex surgical procedure involving en-bloc resection of the parietal and visceral pleura, lung, pericardium, and ipsilateral diaphragm. Small case series of pleural-based sarcoma of predominantly pediatric patients suggest EPP may be a life-prolonging surgical option. We aimed to describe the characteristics and outcomes of adults who underwent EPP at a…

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