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Research

Lumen loss in the first year in saphenous vein grafts is predominantly a result of negative remodeling of the whole vessel rather than a result of changes in wall thickness

July 5, 2006

Lau GT, Ridley LJ, Bannon PG, Wong LA, Trieu J, Brieger DB, Lowe HC, Freedman BS, Kritharides L Circulation 2006 Jul;114(1 Suppl):I435-40 PMID: 16820615 Abstract BACKGROUND: The use of saphenous vein grafts (SVG) in coronary artery bypass surgery is established but little is known of SVG remodeling during the first year in vivo. METHODS AND…

Concentrations of iron correlate with the extent of protein, but not lipid, oxidation in advanced human atherosclerotic lesions

April 24, 2006

Stanley N, Stadler N, Woods AA, Bannon PG, Davies MJ Free Radic. Biol. Med. 2006 May;40(9):1636-43 PMID: 16632123 Abstract Previous studies have provided compelling evidence for the presence of oxidized proteins and lipids in advanced human atherosclerotic lesions. The catalyst responsible for such oxidation is unknown and controversial. We have previously provided evidence for elevated…

Pulmonary hypertension due to isolated metastatic squamous cell carcinoma thromboemboli

March 31, 2006

Wilson MK, Granger EK, Preda VA Heart Lung Circ 2006 Apr;15(2):143-5 PMID: 16412689 Abstract Pulmonary hypertension as the initial presentation of occult malignancy is extremely rare. The differential diagnosis of pulmonary hypertension due to arterial tumour embolism is often overlooked and deserves contemplation. Our case report details the presentation of cardiorespiratory decompensation from an assumed…

Massive immature mediastinal teratoma extending into the left pleural cavity

December 14, 2005

McLeod NP, Vallely MP, Mathur MN Heart Lung Circ 2005 Mar;14(1):45-7 PMID: 16352251 Abstract We report a case of a massive mediastinal teratoma in an 18-year-old woman who presented with a short history of exertional dyspnoea. The tumor arose from the left lobe of the thymus and extended into the left pleural cavity, completely compressing…

Coronary artery to the left atrial fistula after resection of atrial appendages

July 27, 2004

Nguyen-Do P, Bannon P, Leung DY Ann. Thorac. Surg. 2004 Aug;78(2):e26-7 PMID: 15276584 Abstract We report the case of a fistula formation between the left circumflex coronary artery draining into the left atrium as a complication of radiofrequency cardio-ablation and resection of the atrial appendages. This complication was diagnosed with the use of transesophageal echocardiography…

Sodium-hydrogen exchanger inhibition, pharmacologic ischemic preconditioning, or both for extended cardiac allograft preservation

September 22, 2003

Ryan JB, Hicks M, Cropper JR, Garlick SR, Kesteven SH, Wilson MK, Feneley MP, Macdonald PS Transplantation 2003 Sep;76(5):766-71 PMID: 14501850 Abstract BACKGROUND: The aim of this study was to determine the efficacy of cariporide (a sodium-hydrogen exchanger inhibitor), BMS180448 (a pharmacologic ischemic preconditioning agent), and the combination thereof, as adjuvant therapies for extended cardiac…

Functional evidence of reversible ischemic injury immediately after the sympathetic storm associated with experimental brain death

August 11, 2003

Ryan JB, Hicks M, Cropper JR, Garlick SR, Kesteven SH, Wilson MK, Feneley MP, Macdonald PS J. Heart Lung Transplant. 2003 Aug;22(8):922-8 PMID: 12909474 Abstract BACKGROUND: Acute brain death from increased intracranial pressure results in a transient increase in myocardial adenosine and lactate, which indicates that oxygen demand exceeds oxygen delivery during the sympathetic “storm”….

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