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Research

Surgical Pulmonary Embolectomy: Experience in a Series of 37 Consecutive Cases

July 17, 2016

Edelman JJ, Okiwelu N, Anvardeen K, Joshi P, Murphy B, Sanders LH, Newman MA, Passage J Heart Lung Circ 2016 Dec;25(12):1240-1244 PMID: 27423976 Abstract BACKGROUND: Massive pulmonary embolism is a poorly tolerated condition. Treatment options in this condition include anticoagulation and primary reperfusion therapy – systemic thrombolysis, catheter based treatments or surgical embolectomy. There is…

The Aortic Root Replacement Procedure: 12-year Experience from the Australian and New Zealand Society of Cardiac and Thoracic Surgeons Database

June 8, 2016

Dhurandhar V, Parikh R, Saxena A, Vallely MP, Wilson MK, Black DA, Tran L, Reid CM, Bannon PG Heart Lung Circ 2016 Dec;25(12):1245-1251 PMID: 27269475 Abstract BACKGROUND: The aortic root replacement procedure (ARR), is often considered the gold standard in the management of aortic root and ascending aorta aneurysms. Our aim was to review the…

KCa1.1, a calcium-activated potassium channel subunit alpha 1, is targeted by miR-17-5p and modulates cell migration in malignant pleural mesothelioma

June 1, 2016

Cheng YY, Wright CM, Kirschner MB, Williams M, Sarun KH, Sytnyk V, Leshchynska I, Edelman JJ, Vallely MP, McCaughan BC, Klebe S, van Zandwijk N, Lin RC, Reid G Mol. Cancer 2016 Jun;15(1):44 PMID: 27245839 Abstract BACKGROUND: Malignant pleural mesothelioma (MPM) is an aggressive, locally invasive, cancer elicited by asbestos exposure and almost invariably a…

Best Practice BioBanking of Human Heart Tissue

March 21, 2016

Lal S, Li A, Allen D, Allen PD, Bannon P, Cartmill T, Cooke R, Farnsworth A, Keogh A, Dos Remedios C Biophys Rev 2015 Dec;7(4):399-406 PMID: 26998172 Abstract This review provides a guide to researchers who wish to establish a biobank. It also gives practical advice to investigators seeking access to samples of healthy or…

The Benefits and Pitfalls of the Use of Risk Stratification Tools in Cardiac Surgery

February 29, 2016

Saxena A, Dhurandhar V, Bannon PG, Newcomb AE Heart Lung Circ 2016 Apr;25(4):314-8 PMID: 26857968 Abstract Risk assessment tools are increasingly used in surgery. In cardiac surgery, risk models are used for patient counselling, surgical decision-making, performance benchmarking, clinical research, evaluation of new therapies and quality assurance, among others. However, they have numerous disadvantages which…

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